Taxomic and Functional Characterization of Human Gut Microbes Involved in Dietary Plant Lignan Metabolism

Dietary plant lignans, such as secoisolariciresinol diglucoside (SDG), are metabolized to the enterolignans, enterodiol (END) and enterolactone (ENL), by gut microbes. Evidence suggests that enterolignans may reduce risk of cardiovascular disease and several forms of cancer. Our aim was to characterize the microbial community involved in enterolignan production by using an in vitro batch culture system to enrich for lignan-metabolizing organisms.

Materials Available

• Abstract

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Project Type(s): Master's Thesis

Author(s): Isaac Elkon

Program(s): Master of Science

Year: 2015

Adviser(s):

• Johanna W. Lampe